The most educational and complete medical simulator ever madeAI Virtual Patient Simulator for OSCE Practice
Free to start: 30 free AI patient cases, then 10 free foreverI believe it is the best medical simulator because it goes straight to what matters: talking to the patient, examining them and learning from every mistake. As the line often attributed to Einstein goes, “everything should be made as simple as possible, but not simpler.”
— Alejandro Friant, creator of Making Synapses
The most advanced AI patient simulator for OSCE practice. Talk to an AI patient, by voice or by typing. Take the history, examine with your hands and tools, and get an AI-scored checklist with instant feedback. 705 AI clinical cases in 5 languages for MD, DO, PA, nursing and EMS students, on PC and VR.
No card. Sign in with your favorite platform: Steam, Epic, Meta, Apple or Google. You can unify your platforms thanks to Epic.
If you think something here does not reflect reality, please don't hesitate to contact us.
AI patients for every program
Talk to the patient, examine, and get your score and feedback the moment you finish: every Making Synapses case is a full clinical encounter.
No other simulator brings all of this together.
AI patients, PC and VR, multiplayer and free to start: all in one simulator.
See how it works →Talk to your patient
Ask your questions by voice or by typing. The AI patient understands you and answers out loud, like a real person, in your language. Each case gets a random personality: some patients talk all the time, others barely answer.
How you talk to the patient →Instant feedback
When you close the encounter, the Making Synapses AI Attending scores your checklist from 0 to 100% and tells you what you did well and what you missed.
See how you are scored →AI clinical cases
Cases for MD / DO, PA, nursing and EMS, built around USMLE, COMLEX-USA, PANCE, NCLEX and NREMT content, in English, Spanish, French, German and Chinese.
See the 705 cases →Exam day, before exam day
Press OSCE exam and meet a patient you did not choose, with no hints and a time limit, just like the real station.
What the OSCE mode is →Create your own OSCE
Another country or exam? Write your own cases and checklists, in your language, and practice them with an AI patient, on your own or with your group. Also for educators.
Create your own OSCE →Free to start
30 free AI patient cases to play; each case you play uses one. After that, 10 cases stay free forever. Subscribe when you want the whole library.
See the free cases →If you think something here does not reflect reality, please don't hesitate to contact us.
Every case is scored. Every score counts.
The moment you close the encounter, Making Synapses scores your checklist. Your best Test score of each case adds up to your Medical Score, the number that ranks you in your continent and in the world.
- 0 to 100% per case. Each step has its weight, with steps you can do in any order and steps where one of several options is right.
- Critical fails count. A sharp that does not go straight to the container, used material left on the patient or dirty tools not thrown away fail the station, like in the real exam.
- Medical Score. The sum of your best Test score of each case: it grows when you cover more cases and do them well.
- Cross-platform. One score on PC, VR headset, phone and tablet, tied to your account: sign in with Steam, Epic, Meta, Apple or Google.
- Your progress. Every attempt, your most common mistakes and how well you master each case.
Blocky, a patient for every case.
One character made of blocks that becomes any patient: body, age, clothes and signs change so you can practice every technique of the exam.
- 12 patients. Man, woman, pregnant woman, teenagers, children and a baby.
- Signs you can see. Pallor, cyanosis, jaundice, rash, pain and facial palsy on the face and skin.
- Combine it yourself. Body, clothes, hairstyle, expression and stretcher, in 3D.
Practice your OSCE
Making Synapses is a virtual OSCE simulator for medical, physician assistant, nursing and EMS students, and for anyone who wants to have fun with a medical game like this one. Play solo or multiplayer, and if you want, an educator runs the room. Every case runs as an OSCE station, and the OSCE exam button gives you a patient you did not choose, like the real exam.
Pick your program
Medicine (MD, DO), Physician Assistant (PA), Nursing (RN, PN, NP) or EMS (EMT, Paramedic). Each program has its own cases.
→Press OSCE exam
Making Synapses picks a random patient from your program and starts the checklist in Test mode: no hints and a time limit.
→Do the encounter
Talk to the AI patient by voice or by typing: introduce yourself, gain consent, take the history, examine with your hands and tools, and close the encounter.
→Get your score
The Making Synapses AI Attending scores your checklist from 0 to 100% with instant feedback, and every attempt is saved in your account, so you can see how you improve before your exam.
→On PC and VR. Train on your own, write your own cases, or join your school and play the cases your educator picks.
Getting ready? Read our OSCE exam tips and what to expect at OSCE stations, or browse the Making Synapses Blog.
Find your exam and your program
Built for U.S. health science programs
Making Synapses cases are built around the exams and standards your students prepare for. Every case shows the exam content areas it trains.
Medical Doctor / Doctor of Osteopathic Medicine
Clinical conditions from the USMLE Content Outline and the COMLEX-USA Master Blueprint, training the AAMC Core EPAs: history, physical exam and differential diagnosis.
Programs →Physician Assistant / Associate
Scenarios built around the NCCPA PANCE Content Blueprint, for patient-centered practice before the certifying exam.
Programs →Nursing
Clinical judgment practice built around the 2026 NCLEX-RN Test Plan and the NCLEX-PN Test Plan. The NCSBN National Simulation Study supports quality simulation for up to half of clinical hours.
Programs →Emergency Medical Services
Scenarios built around the National EMS Education Standards (NHTSA), the NASEMSO National Model EMS Clinical Guidelines (version 3, 2022) and the NREMT exam.
Programs →Simulation best practice
Sessions follow the INACSL Healthcare Simulation Standards of Best Practice: prebriefing, facilitation, debriefing and evaluation.
Standards →Virtual OSCE stations
Every case runs as an OSCE station: one patient, a step-by-step checklist and a score from 0 to 100%. Test mode gives each student a standardized encounter, and every attempt is saved for the educator.
Exams →Making Synapses cases are written by Alehundred Studios based on the public content outlines and guidelines linked above. Making Synapses is not affiliated with, sponsored by or endorsed by FSMB, NBME, NBOME, AAMC, NCCPA, NCSBN, the National Registry of EMTs, NASEMSO, NHTSA or INACSL. USMLE, COMLEX-USA, PANCE, NCLEX, NCLEX-RN, NCLEX-PN and NREMT are trademarks of their respective owners and are used only to describe the content each case trains.