Hematology conditions flashcards
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Twenty flashcards on common blood conditions: key findings, labs, tests and first treatment.
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20 cards
- Microcytic anemia with low ferritin?
- Iron deficiency anemia.
- Iron deficiency in an older man: likely source?
- GI blood loss; evaluate with colonoscopy and upper endoscopy.
- Microcytic anemia with normal iron studies and target cells?
- Thalassemia trait.
- Sickle cell pain crisis: first treatment?
- IV fluids, fast opioid pain control, oxygen if hypoxic.
- Why is fever urgent in a child with sickle cell disease?
- Functional asplenia raises the risk of serious bacterial infection.
- Drug that reduces sickle cell crises?
- Hydroxyurea.
- Hemolysis after fava beans or sulfa drugs?
- G6PD deficiency.
- Positive direct Coombs test with spherocytes?
- Autoimmune hemolytic anemia.
- Boy with joint bleeding, long PTT and normal PT?
- Hemophilia A or B.
- Isolated low platelets with petechiae in a well child after a virus?
- Immune thrombocytopenia.
- Philadelphia chromosome t(9;22)?
- Chronic myelogenous leukemia.
- Targeted therapy for CML?
- Tyrosine kinase inhibitor such as imatinib.
- Most common childhood cancer?
- Acute lymphoblastic leukemia.
- Painless enlarged node with Reed-Sternberg cells?
- Hodgkin lymphoma.
- CRAB features of multiple myeloma?
- High calcium, renal failure, anemia, bone lesions.
- Test that shows a monoclonal spike in myeloma?
- Serum protein electrophoresis.
- Itching after a hot shower, high hemoglobin, JAK2 mutation?
- Polycythemia vera.
- Bronze skin, diabetes and liver disease with high ferritin?
- Hemochromatosis; treat with phlebotomy.
- Neutrophil count that defines severe neutropenia?
- Below 500 cells/microL.
- Fever with severe neutropenia: action?
- Blood cultures and broad-spectrum IV antibiotics within 1 hour.