Immune system anatomy flashcards
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Twenty flashcards on the immune system: lymphoid organs, innate defenses, T and B cells, antibodies, vaccines and allergy.
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20 cards
- Where does lymph return to the blood?
- The subclavian veins, mainly through the thoracic duct.
- Largest lymphoid organ?
- Spleen.
- Where do T cells mature?
- Thymus.
- Where do B cells mature?
- Bone marrow.
- Main infection risk after splenectomy?
- Encapsulated bacteria such as pneumococcus, meningococcus and Hib.
- First physical barrier against infection?
- Intact skin and mucous membranes.
- First white cells to reach an acute bacterial infection?
- Neutrophils.
- Cell that kills virus-infected cells without prior exposure?
- Natural killer (NK) cell.
- Role of CD4 T cells?
- Helper cells that coordinate the immune response.
- Role of CD8 T cells?
- Cytotoxic cells that kill infected and abnormal cells.
- MHC class I presents antigen to?
- CD8 T cells.
- MHC class II presents antigen to?
- CD4 T cells.
- First antibody made in a new infection?
- IgM.
- Antibody that crosses the placenta?
- IgG.
- Main antibody in breast milk and mucus?
- IgA.
- Antibody that arms mast cells in allergy?
- IgE.
- How does a vaccine protect?
- It trains memory B and T cells to respond fast to the real germ.
- First drug for anaphylaxis?
- IM epinephrine in the outer thigh.
- What fails in autoimmune disease?
- Self-tolerance, so the immune system attacks the body's own tissue.
- Driver of acute cellular transplant rejection?
- Recipient T cells reacting to donor HLA antigens.